I loved being a Vampire in the Elder Scrolls. Was truly a fun part of the game. I don't really see it working in an MMO though. I see loads more advantages than disadvantages from what you've posted.
In the essence Vampires are strong and unkillable unless faced with the tools you mentioned, but I think it would make the game more a Rock, Paper, Scissors game. Comparing a Vampire to the Rock, other classes to the Scissors and lastly normal classes in possession of a Vampire killing tool is Paper.
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